Skip to main content

PHYTOCHEMISTRY OF SOURSOP AND ITS MEDICINAL USES

 The phytochemistry of Annona muricata L. (Laxmanphal)




There are sufficient reasons that Soursop is gaining its popularity in the Health Sector. Soursop is rich in various phytochemicals, Vitamins and minerals that are proved to be helpful in eliminating bad cells. It provide vigour and vitality to the body, helping immune system to deal with the chronic diaseases including Cancer. Inflammation is also prerequisite for the developemnt of various Cancers. Soursop is known to inhibit the cell proliferation and to decrease the tumor growth. Anti-inflammatory effect is also a beneficial and effective strategy in the management of solid Cancers through inhibiting the site of inflammation.  


Annona muricata shows medicinal properties which include anticancer (25%), antiulcer (17%), antidiabetic (14%), antiprotozoal (10%), antidiarrhea (8%), antibacterial (8%), antiviral (8%), antihypertensive (6%), and wound healing (4%). 

Annona muricata (Laxman phal) fruit, bark, leaves, and roots contain major bioactive components such as Annonaceous Acetogenin, Alkaloids, and Flavonoids. They also contain secondary metabolites such as terpenoids, saponins, coumarins, lactones, anthraquinones, glycosides, tannins, and phytosterols. Additionally, the plant contains vitamins A, B1, B2, B3, C and E. Also, minerals such as Potassium (K), Calcium (Ca), Sodium (Na), Copper (Cu), Iron (Fe), and Magnesium (Mg).    
Ref : Mutakin, M.; Fauziati, R.; Fadhilah, F.N.; Zuhrotun, A.; Amalia, R.; Hadisaputri, Y.E. Pharmacological Activities of Soursop (Annona muricata Lin.). Molecules 2022, 27, 1201. https://doi.org/10.3390/ molecules27041201






Comments

Post a Comment

Popular posts from this blog

DEFECTIVE APOPTOSIS - A CANCER CELLS DEVELOPING PROCESS

A NORMAL APOPTOSIS PROCESS APOPTOSIS Apoptosis is a Greek word, meaning to drop off. This term is more relevantly used at the cellular level as the 'cell death' on receiving a certain stimulus. Apoptosis is an important phenomenon that plays an important role in the pathogenesis of many diseases. Low or high rates of Apoptosis are culprits in some degenerative diseases. Cancer is a cellular condition where the rate of Apoptosis is less, resulting in malignant cells that will not die, giving rise to a lump of cells, termed Cancer. In Cancer treatment, targeting Apoptosis in Cancer cells is an important aspect. Defective Apoptotic pathways play a crucial role in Carcinogenesis and can be tackled with targeted Apoptosis with the help of some nutraceutical products. Soursop fruits are rich in Acetogenins, which are known to be selectively toxic to Cancer cells.
Post a Comment
Read more

ANTIMICROBIAL PROPERT OF SOURSOP

  Soursop is appreciated for its high effectivity to fight against Cancer. Some studies reveal that Soursop contains antimicrobial properties as well. Antimicrobial property Soursop can combat various bacterial and parasitic infections. This effect is largely due to the presence of bioactive compounds like Acetogenins, Flavonoids, and Alkaloids in the Soursop fruit and leaves extract. These compounds destroy the integrity of microbial cell membranes and inhibit essential enzymes there by preventing the growth and proliferation of pathogen. The study indicates the Soursop fruit and leaves extracts are effective in treating infections caused by resistant strains making them a promising alternative to conventional antibiotics. Soursop shows antimicrobial efficacy was evaluated using the disc diffusion method against  Streptococcus mutans ,  Streptococcus mitis ,  Porphyromonas gingivalis ,  Prevotella intermedia , and  Candida albicans in laboratory con...
Post a Comment
Read more

ANTI INFLAMMATORY PROPERTY OF SOURSOP

  Due to significant side effects of steroid and non steroidal Anti-inflammatory Drugs (NSAID), there is an increasing interest in herbal remedies that have been in use for many years to minimize pain and inflammation. The great number of natural compounds work similarly to that of the NSAIDs. The mechanism of antinociception (reduced sensitivity to pain) has been shown to inhibit cyclooxygenase (COX) and lipoxygenases (LOX) through inflammatory mediators such as flavonoids present in the plant extract. The anti-inflammatory effects of Annona muricata are thus demonstrated to occur through suppression of inflammatory mediators. A. muricata produced dose-dependent and significant results, which were comparatively similar to the inhibition of inflammatory pain produced by morphine (96.08%) standard reference drug. The effect of the extract in this phase suggests that it may have an anti-inflammatory property. In conclusion, findings from the results of the studies showed th...
Post a Comment
Read more