Skip to main content

SOURSOP ON DIABETES


                            ANTIDIABETIC PROPERTIES OF SOURSOP

After every meal, there is a rise in the blood sugar due to the breakdown of carbohydrates into Glucose, which enters blood bloodstream. In healthy individuals, after about an hour post meal, blood glucose levels peak and return to normal within 2 to 3 hours, with levels rarely exceeding 140 mg/dL. In people with diabetes, this rise can be more pronounced and prolonged, sometimes exceeding 180 mg/dL. 

Soursop fruit and plant parts have been used for the management of Diabetes for years. The folkloric use in Diabetes is supported by the fact that, studies carried out on Soursop in vitro, it has been found that Soursop fruit and Soursop plant part extracts show inhibitory effect on 𝛼-amylase and 𝛼-glucosidase.

Reducing the postprandial hyperglycemia is an important strategy for type 2 Diabetes management. Several studies have shown that α-amylase and α-glucosidase activity significantly influence blood glucose levels. Therefore, their inhibition significantly reduces the postprandial increase of blood glucose. Studies have shown that 𝛼-amylase and 𝛼-glucosidase inhibitory effect of plant foods is attributed to their phenolic constituents. Phenol and flavonoid content found in Soursop fruit and Soursop plant parts exhibited the highest 𝛼-amylase and 𝛼-glucosidase inhibitory effects. Thus, Soursop helps regularise the blood sugar effectively.

 

Reference : S. S. Nair, V. Kavrekar, and A. Mishra, “In vitro studies on alpha amylase and 𝛼 glucosidase inhibitory activities of selected plant extracts,” European Journal of Experimental Biology, vol. 3, no. 1, pp. 128–132, 2013.


Comments

Post a Comment

Popular posts from this blog

ANTIVIRAL PROPERTY OF SOURSOP

  A nnona muricata  L. is a tropical tree that is used in traditional medicine around the world. The high content of flavonoid, alkaloid, acetogenin, phenolic, and lipophilic compounds of this tropical tree forms the basis of its traditional medical uses. According to 49 research articles studied, the pharmacological properties of Soursop are reported to include 8% antiviral properties. Ethanolic extracts from the stem and bark of  A. muricata  showed in vitro antiviral activity against herpes simplex virus (ref. Padma, P.; Pramod, N.P.; Thyagarajan, S.P.; Khosa, R.L. Effect of the Extract of Annona muricata and Petunia Nyctaginiflora on Herpes Simplex Virus. J. Ethnopharmacol. 1998, 61, 81–83.) Acetogenins such as annomuricin a, annomuricin b, annomuricin c, muricatocin c, muricatacin, cis-annonacin, annonacin-10-one, cis-goniothalamicin, arianacin, and javoricin were shown to possess good inhibitory activity against SARS-CoV-2 spike proteins (in silico). Cis-a...
Post a Comment
Read more

ANTI INFLAMMATORY PROPERTY OF SOURSOP

  Due to significant side effects of steroid and non steroidal Anti-inflammatory Drugs (NSAID), there is an increasing interest in herbal remedies that have been in use for many years to minimize pain and inflammation. The great number of natural compounds work similarly to that of the NSAIDs. The mechanism of antinociception (reduced sensitivity to pain) has been shown to inhibit cyclooxygenase (COX) and lipoxygenases (LOX) through inflammatory mediators such as flavonoids present in the plant extract. The anti-inflammatory effects of Annona muricata are thus demonstrated to occur through suppression of inflammatory mediators. A. muricata produced dose-dependent and significant results, which were comparatively similar to the inhibition of inflammatory pain produced by morphine (96.08%) standard reference drug. The effect of the extract in this phase suggests that it may have an anti-inflammatory property. In conclusion, findings from the results of the studies showed th...
Post a Comment
Read more

ANTI HYPERTENSIVE ACTIVITY OF SOURSOP

  Annona muricata  L. is a tropical tree that is used in traditional medicine around the world. The high content of flavonoid, alkaloid, acetogenin, phenolic, and lipophilic compounds of this tropical tree forms the basis of its traditional medical uses. According to 49 research articles studied, the pharmacological properties of Soursop are reported to include 6% antihypertensive properties. In a study carried out in Jamaica, it was found that Annona muricata shows antioxidant and antihypertensive properties through Angiotensin-I-converting enzymes in vitro. The suggested hypotensive mechanism of A. muricata takes action through the blockage of calcium ion channels, that lowers the blood pressure. The hypotensive effects of A. muricata are not mediated through muscarinic, histaminergic, adrenergic, and nitric oxide pathways, but through peripheral mechanisms involving antagonism of Ca(2+). (REF.  Nwokocha, C.R.; Owu, D.U.; Gordon, A.; Thaxter, K.; Mccalla, G.; Ozo...
Post a Comment
Read more