NUTRITIONAL PROPERTIES OF SOURSOP

Soursop is loaded with various Minerals and Vitamins, being the reason why Soursop is most popular with health conscious people as well as those with poor health conditions due to serious disease like Cancer.

Minerals are the earth elements found in the foodstuff and are necessary for body growth and normal body functioning.

Magnesium (Mg) helps regulate muscle and nerve function. It is generally regarded as good for muscle and bone health. It helps to maintain blood sugar levels and stomach health.

Calcium (Ca) plays an important role in muscle contraction and nerve functioning. It is important to keep the bones and teeth strong and healthy.

Iron (Fe) is the integral part of Haemoglobin, responsible for the conduction of Oxygen. It keeps up the immune system and helps in energy production.

Potassium (K) is important in lowering blood pressure and, therefore important in maintaining blood pressure.

Vitamins are the group of substances required for normal cell functioning, overall body growth and development.

Vitamin A is a fat soluble vitamin, important for normal vision, the immune system, and overall body growth and development.

Vitamin B1 (Thiamine) helps the nervous system function normally. It strengthens the immune system.

Vitamin B2 (Riboflavin) helps the body to convert carbohydrates into glucose, which is used to produce energy. Hence it helps to maintain the energy levels in the body.

Vitamin B3 (Niacin) plays an important role in maintaining the health of your heart, blood vessels, and metabolism. It helps to lower cardiovascular disease risk.

Vitamin C functions as an Antioxidant. It has immense importance in maintaining the immune system. It helps to heal the wound.

Vitamin E functions as an Antioxidant. It reduces inflammation and improves immune function. It is necessary for healthy skin and hair.

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SOURSOP IN CANCER ADJUVANT THERAPY

Annonaceous Acetogenins are the most valuable phytochemicals present in Soursop/ Laxmanphal, scientifically known as Annona muricata . Annonaceous acetogenins typically are derivatives of long chain fatty acids that are selectively toxic to Cancer cells, including multidrug resistant Cancer cells. Scientific research carried out by Hadisaputri et al (2021) conclude that Annona muricata leaf extract is responsible for the induction of apoptosis of breast cancer cells. This apoptosis is majorly due to reduction in the integrity of mitochondrial cells. Cancer cells may develop Multi Drug Resistance (MDR), a phenomenon in which Cancer cells develops resistivity against the the specific drug being used in the Cancer treatment. Acetogenins (ACG) in Soursop are found to be cytotoxic to these Drug Resistant Cancer cells. As a result, these Cancer cells undergo death and decay, preventing the spread of Cancer to other parts of body (Metastasis). Annonaceous acetogenins induce cy...

DEFECTIVE APOPTOSIS - A CANCER CELLS DEVELOPING PROCESS

A NORMAL APOPTOSIS PROCESS APOPTOSIS Apoptosis is a Greek word, meaning to drop off. This term is more relevantly used at the cellular level as the 'cell death' on receiving a certain stimulus. Apoptosis is an important phenomenon that plays an important role in the pathogenesis of many diseases. Low or high rates of Apoptosis are culprits in some degenerative diseases. Cancer is a cellular condition where the rate of Apoptosis is less, resulting in malignant cells that will not die, giving rise to a lump of cells, termed Cancer. In Cancer treatment, targeting Apoptosis in Cancer cells is an important aspect. Defective Apoptotic pathways play a crucial role in Carcinogenesis and can be tackled with targeted Apoptosis with the help of some nutraceutical products. Soursop fruits are rich in Acetogenins, which are known to be selectively toxic to Cancer cells.

ANTIMICROBIAL PROPERT OF SOURSOP

Soursop is appreciated for its high effectivity to fight against Cancer. Some studies reveal that Soursop contains antimicrobial properties as well. Antimicrobial property Soursop can combat various bacterial and parasitic infections. This effect is largely due to the presence of bioactive compounds like Acetogenins, Flavonoids, and Alkaloids in the Soursop fruit and leaves extract. These compounds destroy the integrity of microbial cell membranes and inhibit essential enzymes there by preventing the growth and proliferation of pathogen. The study indicates the Soursop fruit and leaves extracts are effective in treating infections caused by resistant strains making them a promising alternative to conventional antibiotics. Soursop shows antimicrobial efficacy was evaluated using the disc diffusion method against Streptococcus mutans , Streptococcus mitis , Porphyromonas gingivalis , Prevotella intermedia , and Candida albicans in laboratory con...

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