SOURSOP TREE GROWTH PROGRESS

On favorable conditions, the Soursop seeds germinate after about 45 days. Successful germination enables further growth of the sapling which may reach to 1-2 feet after about one year.

These small saplings are protected from the external physical damage and allowed to grow. Soursop plant attains about 3-6 feet within a span of about 2 years.

With abundant sunlight and proper care with fertilizers and minimal pesticides, Soursop tree grows upto 7-10 feet and mature enough to get the flowering. These flowers on successful pollination grows into fruit. Soursop tree can bear upto 12-15 kg of fruits after 3-4 years of growth. With the help of proper fertilizers, after 5 years of growth, Soursop can bear upto 30-35 kg per tree in a single season.

Intercrops like Onion, Tomato, Chilly or any other herb plant can be grown simultaneously to increase the gains. The fertilizers applied to intercrops are also shared with the Soursop tree, helping Soursop trees to grow more vigorously

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SOURSOP IN CANCER ADJUVANT THERAPY

Annonaceous Acetogenins are the most valuable phytochemicals present in Soursop/ Laxmanphal, scientifically known as Annona muricata . Annonaceous acetogenins typically are derivatives of long chain fatty acids that are selectively toxic to Cancer cells, including multidrug resistant Cancer cells. Scientific research carried out by Hadisaputri et al (2021) conclude that Annona muricata leaf extract is responsible for the induction of apoptosis of breast cancer cells. This apoptosis is majorly due to reduction in the integrity of mitochondrial cells. Cancer cells may develop Multi Drug Resistance (MDR), a phenomenon in which Cancer cells develops resistivity against the the specific drug being used in the Cancer treatment. Acetogenins (ACG) in Soursop are found to be cytotoxic to these Drug Resistant Cancer cells. As a result, these Cancer cells undergo death and decay, preventing the spread of Cancer to other parts of body (Metastasis). Annonaceous acetogenins induce cy...

DEFECTIVE APOPTOSIS - A CANCER CELLS DEVELOPING PROCESS

A NORMAL APOPTOSIS PROCESS APOPTOSIS Apoptosis is a Greek word, meaning to drop off. This term is more relevantly used at the cellular level as the 'cell death' on receiving a certain stimulus. Apoptosis is an important phenomenon that plays an important role in the pathogenesis of many diseases. Low or high rates of Apoptosis are culprits in some degenerative diseases. Cancer is a cellular condition where the rate of Apoptosis is less, resulting in malignant cells that will not die, giving rise to a lump of cells, termed Cancer. In Cancer treatment, targeting Apoptosis in Cancer cells is an important aspect. Defective Apoptotic pathways play a crucial role in Carcinogenesis and can be tackled with targeted Apoptosis with the help of some nutraceutical products. Soursop fruits are rich in Acetogenins, which are known to be selectively toxic to Cancer cells.

ANTIMICROBIAL PROPERT OF SOURSOP

Soursop is appreciated for its high effectivity to fight against Cancer. Some studies reveal that Soursop contains antimicrobial properties as well. Antimicrobial property Soursop can combat various bacterial and parasitic infections. This effect is largely due to the presence of bioactive compounds like Acetogenins, Flavonoids, and Alkaloids in the Soursop fruit and leaves extract. These compounds destroy the integrity of microbial cell membranes and inhibit essential enzymes there by preventing the growth and proliferation of pathogen. The study indicates the Soursop fruit and leaves extracts are effective in treating infections caused by resistant strains making them a promising alternative to conventional antibiotics. Soursop shows antimicrobial efficacy was evaluated using the disc diffusion method against Streptococcus mutans , Streptococcus mitis , Porphyromonas gingivalis , Prevotella intermedia , and Candida albicans in laboratory con...

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