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ANTIDIABETIC EFFECT OF SOURSOP

  

LAXMANPHAL - SOURSOP - Annona muricata exhibits Antidiabetic activity.

A. muricata fruit extracts were reported to have excellent antioxidant and antidiabetic properties by inhibiting key enzymes relevant to type 2 diabetes mellitus, such as α-amylase and α-glucosidase, in vitro.

It contains Flavonoids that inhibit α-glucosidase activity through hydroxylation bonding that suppresses carbohydrate hydrolysis and glucose absorption and inhibits carbohydrate metabolism into glucose.

The fruit pulp and leaf extract shows high effectiveness in inhibiting α-amylase and α-glucosidase, which minimizes the rate of glucose assimilation into the bloodstream after feeding, as compared with the standard drug. (Agu, K.C.; Eluehike et al., Inhibition of α-Amylase and α-Glucosidase Activities. Clin. Phytosci., 5, 1–13, 2019)


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