Soursop Information Blog for Awareness

                                    ANTIDIABETIC PROPERTIES OF SOURSOP After every meal, there is a rise in the blood sugar due to the breakdown of carbohydrates into Glucose, which enters blood bloodstream. In healthy individuals, after about an hour post meal, blood glucose levels peak and return to normal within 2 to 3 hours, with levels rarely exceeding 140 mg/dL. In people with diabetes, this rise can be more pronounced and prolonged, sometimes exceeding 180 mg/dL.  Soursop fruit and plant parts have been used for the management of Diabetes for years. The folkloric use in Diabetes is supported by the fact that, studies carried out on Soursop in vitro, it has been found that Soursop fruit and Soursop plant part extracts show inhibitory effect on 𝛼 -amylase and 𝛼 -glucosidase. Reducing the postprandial hyperglycemia is an important strategy for type 2 Diabetes managemen...

  Diarrhea is a gastrointestinal disorder caused by bacterial infection. It is characterised by remarkable pain in the abdominal region with watery stools and frequent bowel movements. Antibiotics used as Antidirrhea drugs lose their effectiveness, as bacteria become resistant to the antibiotics. Some traditional plants are widely used as antidiarrheals. Fruit and other plant parts of Soursop - Annona muricata show antidiarrheal activity by inhibiting intestinal motility and secretions that cause diarrhea. F lavonoids, triterpenoids, and saponins of Soursop (Annona  muricata)  play important role in its antidiarrhea activity. 

  Annona muricata  L. is a tropical tree that is used in traditional medicine around the world. The high content of flavonoid, alkaloid, acetogenin, phenolic, and lipophilic compounds of this tropical tree forms the basis of its traditional medical uses. According to 49 research articles studied, the pharmacological properties of Soursop are reported to include 6% antihypertensive properties. In a study carried out in Jamaica, it was found that Annona muricata shows antioxidant and antihypertensive properties through Angiotensin-I-converting enzymes in vitro. The suggested hypotensive mechanism of A. muricata takes action through the blockage of calcium ion channels, that lowers the blood pressure. The hypotensive effects of A. muricata are not mediated through muscarinic, histaminergic, adrenergic, and nitric oxide pathways, but through peripheral mechanisms involving antagonism of Ca(2+). (REF.  Nwokocha, C.R.; Owu, D.U.; Gordon, A.; Thaxter, K.; Mccalla, G.; Ozo...

  A nnona muricata  L. is a tropical tree that is used in traditional medicine around the world. The high content of flavonoid, alkaloid, acetogenin, phenolic, and lipophilic compounds of this tropical tree forms the basis of its traditional medical uses. According to 49 research articles studied, the pharmacological properties of Soursop are reported to include 8% antiviral properties. Ethanolic extracts from the stem and bark of  A. muricata  showed in vitro antiviral activity against herpes simplex virus (ref. Padma, P.; Pramod, N.P.; Thyagarajan, S.P.; Khosa, R.L. Effect of the Extract of Annona muricata and Petunia Nyctaginiflora on Herpes Simplex Virus. J. Ethnopharmacol. 1998, 61, 81–83.) Acetogenins such as annomuricin a, annomuricin b, annomuricin c, muricatocin c, muricatacin, cis-annonacin, annonacin-10-one, cis-goniothalamicin, arianacin, and javoricin were shown to possess good inhibitory activity against SARS-CoV-2 spike proteins (in silico). Cis-a...

  ANTIULCER PROPERTIES OF SOURSOP - LAXMANPHAL ( Annona muricata ) Annona muricata contains high concentrations of flavonoids, tannins, and phenolic acid, making it a strong antioxidant, anti-inflammatory, and gastro-protective properties. A survey revealed that the leaves and bark of A. muricata are popularly used to make tea, used in the treatment of gastrointestinal problems such as gastritis, and poor digestion. In a study carried out by (REF. 1), A. muricata has also been reported to improve gastric lesions. The hydroalcoholic extract of A. muricata leaves to treat ulcers in absolute and acidified methanol or indomethacin-induced lesions in rats showed that the extract reduced the ulceration process by activating prostaglandin synthesis as a gastro-protector and suppressed aggressive factors of the gastric mucosa. Another study carried out by (REF. 2)   on A. muricata ethyl acetate extract showed antiulcer activity via ROS-scavenging and gastric wall damage pro...

  Due to significant side effects of steroid and non steroidal Anti-inflammatory Drugs (NSAID), there is an increasing interest in herbal remedies that have been in use for many years to minimize pain and inflammation. The great number of natural compounds work similarly to that of the NSAIDs. The mechanism of antinociception (reduced sensitivity to pain) has been shown to inhibit cyclooxygenase (COX) and lipoxygenases (LOX) through inflammatory mediators such as flavonoids present in the plant extract. The anti-inflammatory effects of Annona muricata are thus demonstrated to occur through suppression of inflammatory mediators. A. muricata produced dose-dependent and significant results, which were comparatively similar to the inhibition of inflammatory pain produced by morphine (96.08%) standard reference drug. The effect of the extract in this phase suggests that it may have an anti-inflammatory property. In conclusion, findings from the results of the studies showed th...